Cadena de frío for the laboratory

As a reference: +2 to +8 °C for vaccines, drugs and reagents in routine use (biomedical refrigerator); -20 to -40 °C for plasma, enzymes and biologicals (freezer); -70/-80 °C for critical long-term biological material such as nucleic acids, cells and biobanks (ultra-low temperature freezer). The material defines the equipment, not the other way around.

Because they guarantee neither uniformity nor stability: they have cold and warm spots, recover slowly after the door is opened, and lack alarms and recording for auditing. Biomedical-grade equipment keeps the temperature homogeneous, alarms on deviations, and documents storage conditions.

With equipment that has good thermal retention, local and remote alarms (audible, remote or to the cloud), continuous temperature recording and, for critical loads, electrical or CO₂/LN2 backup, all within a documented contingency plan.

Installation and operational qualification (IQ/OQ) plus thermal mapping with load and calibrated sensors, and recording compliant with 21 CFR Part 11 where applicable. Inolab, together with Meling and Binder, installs, qualifies and services the entire cold chain in Mexico.