Cribado y selección de clones for the laboratory
An area that groups together equipment for detecting, quantifying and selecting producer cells or clones at the individual level, including secreting-cell analyzers (ELISpot, FluoroSpot) and clone selection workflows.
cribado y selección de clones guide
Vaccinology, oncology (T-cell response), infectious diseases, autoimmunity, development of producer cell lines and assurance of monoclonality in clinical research and biopharmaceuticals.
How to choose cribado y selección de clones
- It depends on the type of assay (ELISpot, FluoroSpot, colony imaging)
- The number of color channels
- The plate format and density
- The image resolution
- The throughput and traceability. Specific values come from the catalog (Sanity)
Frequently asked questions about cribado y selección de clones
What equipment do I need to select high-producing clones?
It depends on the step in the workflow: ELISpot/FluoroSpot analyzers quantify individual secreting cells; imaging systems verify clonality and monitor colony growth. The shared goal is to identify producer clones early and document it.
How do I document monoclonality for a regulatory authority?
With imaging evidence of the well from day zero demonstrating origin from a single cell. Automated imaging systems generate that photographic record, which is increasingly expected in regulatory submissions for producer cell lines.
How much faster is screening compared with the limiting dilution method?
Classic limiting dilution requires several rounds lasting weeks; automated screening with imaging and secretion detection identifies candidates in a fraction of the time and with greater statistical certainty, freeing up months in cell line development.
Are these platforms also useful for antibody research?
Yes: antibody discovery, hybridoma development and characterization of cellular immune response use the same technological basis of secreting-cell detection and colony analysis.
Brands we represent in cribado y selección de clones
Available cribado y selección de clones models
- BioLector XTBeckman Coulter
- Cydem VTBeckman Coulter
- CELLXPRESS.AIMolecular Devices
- ClonePix 2Molecular Devices
- ClonePix 2 mejorado para verificación de la monoclonalidadMolecular Devices
- CloneSelect Imager FLMolecular Devices
- QPix 400Molecular Devices
- QPix 420Molecular Devices
- QPix FLEXMolecular Devices
- QPix LHMolecular Devices
- QPix Select HTMolecular Devices
- QPix Select HT-LHMolecular Devices
- QPix XEMolecular Devices
More biotecnología y biología molecular equipment
- Citometría de flujo
- Lectores de microplacas
- Microarreglos
- Electrofisiología
- Analizadores ELISpot/FluoroSpot
Not sure which one you need? Ask Inolab's AI advisor and get the right cribado y selección de clones recommendation for your application, with real specifications and a quote from a specialist. Back to the advisor ↑